Nuffield Placement 23 - Antibacterial Agents

Supervisor: Mark Ashton
Organisation: Sundland University: Dept. of Pharmacy
Successful Applicant: Chloe Fisher
School: Cramlington Learning Villiage

Research Area: Chemistry / Pharmacy
Length of Project: 6 weeks

Project Outline:

Bacterial resistance to antimicrobial agents is a growing worldwide problem. Many of the recent developments by the pharmaceutical industry have been directed against resistant strains of Gram-positive pathogens, such as Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcal (VRE). Although progress has been made, there is still a strong imperative for the development of new antibacterial agents. The aim of project is to develop novel antimicrobial chemical entities with medical applications and to evaluate their mechanism of action. The student(s) will be involved in the synthesis, purification and characterisation of novel small molecule compounds, working in one of the University's new laboratories. In addition, they will be encouraged to participate in the discovery process by working alongside PhD students and academic staff who are actively engaged in the area of drug discovery and development.

Start Date: 9 July 2012

Requirements: None

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